Interstitial Nephritis

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Contents 1 More Specific Terms 2 Etiology 3 More General Terms 4 Additional Terms 5 References

More Specific Terms

• acute interstitial nephritis
• acute uric acid nephropathy
• chronic interstitial nephritis (analgesic nephropathy, drug-induced chronic interstitial nephritis)
• lead nephropathy
• renal papillary necrosis

Etiology

• acute interstitial nephritis
• analgesic nephropathy*
• papillary necrosis
• toxin- & electrolyte-induced interstitial nephritis

• uric acid nephropathy*
• hypercalcemia
• hypokalemia
• hyperoxaluria

• ethylene glycol
• methoxyflurane
• high doses of ascorbic acid
• vitamin B6 deficiency
• excessive gut absorption in patients with steatorrhea

• cystinosis
• heavy metals*#

• lead
• cadmium
• mercury

• pharmaceutical agents*#

• cyclosporine
• some antibiotics
• radiographic contrast media

• plastics
• pigments
• glass
• electrical equipment manufacturing
• some cigarettes

• other disease associations

• glomerular injury

• lupus nephritis
• mixed cryoglobulinemia
• hypertension
• diabetes mellitus
• Sjogren's syndrome
• Alport's syndrome
• amyloidosis, including myeloma*
• Fabry's disease
• glomerulonephritis (in general)

• Balkan nephropathy (associated with increased incidence of urogenital tumors
• granulomatous nephropathy

• tuberculosis
• sarcoidosis

• neoplasia

• lymphoma
• leukemia

• immune disorders

• hypersensitivity nephropathy*#
• transplant rejection
• AIDS

• vascular disorders

• arteriolar nephrosclerosis
• atheroembolic disease
• sickle cell trait/disease
• acute tubular necrosis*#

• hereditary disorders

• medullary cystic & medullary sponge disease
• polycystic kidney disease

• infectious: acute*# & chronic pyelonephritis
• chronic urinary tract obstruction
• vesiculoureteral reflux*
• radiation nephritis

• * common
• # acute

More General Terms

• nephritis
• renal tubulointerstitial disease

Additional Terms

• hyperoxaluria

References

1. Harrison's Principles of Internal Medicine, 13th ed. Companion Handbook, Isselbacher et al (eds), McGraw-Hill Inc. NY, 1995, pg 829-39
2. Manual of Medical Therapeutics, 28th ed, Ewald & McKenzie (eds), Little, Brown & Co, Boston, 1995, pg 266
3. Mayo Internal Medicine Board Review, 1998-99, Prakash UBS (ed) Lippincott-Raven, Philadelphia, 1998, pg 612
4. Harrison's Principles of Internal Medicine, 13th ed. Isselbacher et al (eds), McGraw-Hill Inc. NY, 1994, pg 1314

interstitial nephritis