Interleukin 20 Receptor Alpha

From Anvita Health Wiki

Contents 1 Function 2 Structure 3 Compartment 4 Alternative-splicing 5 Expression 6 Pathology 7 More General Terms 8 Internet Database 9 References

Function

• IL20RA/ IL20RB dimer is a receptor for IL19, IL20 & IL24
• IL20RA/ IL10RB dimer is a receptor for IL26

Structure

• belongs to the type II cytokine receptor family
• contains 2 fibronectin F3 modules

Compartment

• membrane

Alternative-splicing

• named isoforms=2

Expression

• widely expressed
• highest levels in skin & testis
• high levels in brain

Pathology

• highly expressed in psoriatic skin

More General Terms

• protein subunit
• membrane protein
• glycoprotein

Internet Database

Kegg: [1]
OMIM: 605620
Prosite: [2]
Entrez gene: 53832
UniProt: [3]

References

1. Entrez Gene [4]
2. UniProt [5]

interleukin-20 receptor alpha chain; IL-20R-alpha; IL-20R1; cytokine receptor class-II member 8; cytokine receptor family 2 member 8; CRF2-8; ZcytoR7 (IL20RA, ZCYTOR7, UNQ681/PRO1315)