Integrator Complex Subunit 2

From Anvita Health Wiki

Contents 1 Function 2 Structure 3 Compartment 4 Notes 5 More General Terms 6 Internet Database 7 References

Function

• component of the integrator complex
• phosphorylated upon DNA damage, probably by ATM or ATR

Structure

• belongs to the integrator subunit 2 family

Compartment

• nucleus, membrane

Notes

• uncertain whether Met-1 or Met-9 is the initiator
• orthologous sequences (mouse & chicken) have shorter N-terminus

More General Terms

• protein subunit
• membrane protein
• phosphoprotein

Internet Database

UniProt: [1]

References

UniProt [2]

integrator complex subunit 2 (Int2, INTS2, KIAA1287)