Inappropriate Medications In The Elderly By Disorder
From Anvita Health Wiki
Contents |
Introduction
- Also see Beers criteria
- disorder: heart failure
- drug: disopyramide ( Norpace), high Na+ content drugs
- concern: negative inotrope, fluid retention (respectively)
- severity rating: high
- disorder: hypertension
- drug: phenylpropanolamine, pseudoephedrine, amphetamine
- concern: sympathomimetic effects
- severity rating: high
- disorder: peptic ulcer
- drug: NSAIDs, aspirin
- concern: inhibition of gastroprotective prostaglandins
- severity rating: high
- disorder: seizures
- drug: clozapine ( Clozaril), chlorpromazine ( Thorazine), thioridazine ( Mellaril), thiothixene ( Navane), bupropion ( Wellbutrin)
- concern: may lower seizure threshold
- severity rating: high
- disorder: blood clotting disorders, anticoagulation
- drug: aspirin, NSAIDs, dipyridamole ( Persantine), ticlopidine ( Ticlid), clopidogrel ( Plavix)
- concern: prolonged clotting time, inhibition of platelet activation, increased risk of bleeding
- severity rating: high
- disorder: overflow incontinence
- drug: anticholinergic agents, antihistamines, gastrointestinal antispasmodics, muscle relaxants, oxybutinin ( Ditropan), flovaxate ( Urispas), tricyclic antidepressants, decongestants, tolterodine ( Detrol)
- concern: urinary retention
- severity rating: high
- disorder: stress incontinence
- drug: alpha blockers ( doxazosin, prazosin, terazosin), anticholinergic agents, tricyclic antidepressants ( amitriptyline, imipramine, doxepine), long-acting benzodiazepines
- concern: urinary retention
- severity rating: high
- disorder: arrhythmias
- drug: tricyclic antidepressants ( amitriptyline, imipramine, doxepine)
- concern: proarrhythmic effects, QT prolongation
- severity rating: high
- disorder: insomnia
- drug: docongestants, theophylline, methylphenidatee, MAO inhibitors, amphetamines
- concern: CNS stimulant
- severity rating: high
- disorder: Parkinson's disease
- drug: metoclopramide ( Reglan), conventional antipsychotics, cholinesterase inhibitors
- concern: dopamine antagonists, cholinergic effects
- severity rating: high
- disorder: cognitive impairment
- drug: barbiturates, anticholinergic agents, antispasmodics, muscle relaxants, CNS stimulants: dextroamphetamine (Adderall), methylphenidate ( Ritalin), methamphetamine (Desoxyn), pemolin
- concern: CNS-altering effects
- severity rating: high
- disorder: depression
- drug: benzodiazepines (long-term use), sympatholytic agents: methyldopa ( Aldomet), reserpine, guanethidine ( Ismelin)
- concern: exacerbation of depression
- severity rating: high
- disorder: anorexia or malnutrition
- drug: CNS stimulants: dextroamphetamine (Adderall), methylphenidate ( Ritalin), methamphetamine (Desoxyn), fluoxetine ( Prozac)
- concern: anorexic effect
- severity rating: high
- disorder: falls (see falls in the elderly)
- drug: benzodiazepines, tricyclic depressants ( amitriptyline, imipramine, doxepine)
- concern: ataxia, impaired psychomotor dysfunction, syncope
- severity rating: high
- disorder: hyponatremia
- drug: SSRIs: fluoxetrine ( Prozac), citalopram ( Celexa), fluvoxamine (Luxox), paroxetine ( Paxil) sertraline ( Zoloft)
- concern: SIADH
- severity rating: low
- disorder: obesity drug: olanzapine concern: appetite stimulation severity rating: low
- disorder: COPD
- drug: benzodiazepines, long-acting: chlordiazepoxide ( Librium), diazepam ( Valium), quazepam ( Doral), halazepam ( Paxipam), chlorazepate ( Tranxene), beta-blockers: propranolol
- concern: CNS adverse effect, respiratory depression
- severity rating: high
- disorder: constipation, chronic
- drug: calcium channel blocker, anticholinergic agents, tricyclic antidepressants ( amitriptyline, imipramine, doxepine)
- concern: constipation
- severity rating: low
More General Terms
Additional Terms
References
- Fick DM, Cooper JW, Wade WE, Waller JL, Maclean JR, Beers MH. Updating the Beers criteria for potentially inappropriate medication use in older adults: results of a US consensus panel of experts. Arch Intern Med 2003, 163:2716 PMID: [1]
