Immunoglobulin Superfamily Member 6
From Anvita Health Wiki
Contents |
Structure
- contains 1 Ig-like C2-type domain ( immunoglobulin-like)
Compartment
- membrane
Expression
- expressed in peripheral blood lymphocytes, spleen & lymph node, > thymus, bone marrow & fetal liver
- no expression in non- immune tissues
- induced by TNF-alpha & GM-CSF/ CSF2 in dendritic cells
- down regulation by PMA & ionomycin in monocytes Misc:
- gene localized region associated with inflammatory bowel disease
- coded entirely within the intron of METTL9 which is transcribed in the opposite strand of the DNA
More General Terms
Internet Database
Kegg: [1]
OMIM: 606222
UniProt: [2]
References
UniProt [3]
