Henderson Hasselbalch Equation

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Introduction

* pH = pKa + log ([HCO3-]/[H2CO3]) 
* pH = 6.1 + log ([HCO3-]/[H2CO3]) 
* pH = 61 + log ([HCO3-]/(0.03 x pCO2)) 
*                24 x pCO2 (mm Hg) 
* H+ (nmol/L) =  ----------------- 
*                [HCO3-] (mmol/L)

• Normal acid-base values:

<br>  
*     pCO2 = 38-42 mm Hg 
*  [HCO3-] = 24-28 mmol/L 
*     [H+] = 40 mmol/L 

Additional Terms

• acid-base balance

References

1. Medical Knowledge Self Assessment Program (MKSAP) 11, 14 American College of Physicians, Philadelphia 1998, 2006
2. Clinical Diagnosis & Management by Laboratory Methods, 19th edition, J.B. Henry (ed), W.B. Saunders Co., Philadelphia, PA. 1996, pg 85,150,152

Henderson-Hasselbalch equation