Heme Transporter Hrg1

From Anvita Health Wiki

Contents 1 Function 2 Structure 3 Compartment 4 Alternative-splicing 5 Expression 6 More General Terms 7 Internet Database 8 References

Function

• heme transporter
• regulates intracellular heme availability through the endosomal or lysosomal compartment

Structure

• belongs to the HRG family

Compartment

• endosome membrane
• lysosomal membrane

Alternative-splicing

• named isoforms=2

Expression

• highly expressed in the brain, kidney, heart & skeletal muscle
• moderately expressed in the liver, lung, placenta & small intestine

More General Terms

• carrier protein (transporter)
• membrane protein

Internet Database

OMIM: 612187
UniProt: [1]

References

UniProt [2]

heme transporter HRG1; heme-responsive gene 1 protein homolog; HRG-1; hHRG-1 (HRG1)