Hedgehog Interacting Protein

From Anvita Health Wiki

Contents 1 Function 2 Compartment 3 Alternative-splicing 4 Expression 5 More General Terms 6 Internet Database 7 References

Function

• modulates hedgehog signaling in brain & lung
• interacts with all 3 hedgehog family members: SHH, IHH, DHH

Compartment

• cell membrane; peripheral membrane, secreted

Alternative-splicing

• named isoforms=2

Expression

• widely expressed in fetal & adult tissues
• highest expression in adult heart, liver, pancreas, fetal kidney

More General Terms

• membrane protein
• glycoprotein

Internet Database

OMIM: 606178
Entrez gene: 64399
Prosite: [1]
Prosite: [2]
UniProt: [3]

References

1. Entrez Gene [4]
2. UniProt [5]

hedgehog interacting protein (HHIP, UNQ5825/PRO1964)