Golgi

From Anvita Health Wiki

Contents 1 More Specific Terms 2 Introduction 3 Classification 4 Function 5 More General Terms 6 Additional Terms 7 References

More Specific Terms

• acrosome
• cis-Golgi
• trans-Golgi (trans-Golgi network, TGN)

Introduction

• A stacked array of membranous cisternae & connecting tubules or vesicles between the nucleus & the secretory pole of a cell. It is receives nascent polypeptides from the endoplasmic reticulum, destined for the secretory pathway.

Classification

• cis, trans & intermediate GOLGI compartments have been described

Function

• 3 major functions: [2]

• carbohydrate processing & modification of proteins & lipids moving through the secretory pathway
• protein sorting & transport, receiving membrane from the ER & delivering it to the plasma membrane or other intracellular sites
• membrane scaffold onto which diverse signaling, sorting & cytoskeleton proteins adhere

More General Terms

• organelle

Additional Terms

• Golgi, Camillo

References

1. Stedman's Medical Dictionary 27th ed, Williams & Wilkins, Baltimore, 1999.
2. Altan-Bonnet N, Sougrat R, Lippincott-Schwartz J. Molecular basis for Golgi maintenance and biogenesis. Curr Opin Cell Biol. 2004 Aug;16(4):364-72. Review. PMID: [1]
3. de Graffenried CL, Bertozzi CR. The roles of enzyme localisation and complex formation in glycan assembly within the Golgi apparatus. Curr Opin Cell Biol. 2004 Aug;16(4):356-63. Review. PMID: [2]
4. Colanzi A, Suetterlin C, Malhotra V. Cell-cycle-specific Golgi fragmentation: how and why? Curr Opin Cell Biol. 2003 Aug;15(4):462-7. Review. PMID: [3]
5. Barr FA, Short B. Golgins in the structure and dynamics of the Golgi apparatus. Curr Opin Cell Biol. 2003 Aug;15(4):405-13. Review. PMID: [4]
6. Bankaitis VA, Morris AJ. Lipids and the exocytotic machinery of eukaryotic cells. Curr Opin Cell Biol. 2003 Aug;15(4):389-95. Review. PMID: [5]
7. Ponnambalam S, Baldwin SA. Constitutive protein secretion from the trans-Golgi network to the plasma membrane. Mol Membr Biol. 2003 Apr-Jun;20(2):129-39. Review. PMID: [6]
8. Rabouille C, Jokitalo E. Golgi apparatus partitioning during cell division. Mol Membr Biol. 2003 Apr-Jun;20(2):117-27. Review. PMID: [7]
9. Machamer CE. Golgi disassembly in apoptosis: cause or effect? Trends Cell Biol. 2003 Jun;13(6):279-81. Review. PMID: [8]

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