Glutamate Receptor Epsilon 4

From Anvita Health Wiki

Contents 1 Function 2 Structure 3 Compartment 4 More General Terms 5 Internet Database 6 References

Function

• NMDA receptor subunit
• high Ca+2 permeability
• voltage-dependent sensitivity to Mg+2
• mediated by glycine
• interacts with PDZ domains of INADL & DLG4
• forms heteromeric channel of

• zeta subunit ( GRIN1)
• epsilon subunit ( GRIN2A, GRIN2B, GRIN2C or GRIN2D)
• 3rd subunit ( GRIN3A or GRIN3B)

Structure

• belongs to the glutamate-gated ion channel (TC 1.A.10) family

Compartment

• cell membrane
• cell junction, synapse, postsynaptic cell membrane

More General Terms

• glutamate receptor epsilon
• phosphoprotein
• glycoprotein

Internet Database

Kegg: [1]
OMIM: 602717
UniProt: [2]
Entrez gene: 2906

References

1. UniProt [3]
2. Liu Y, Zhang J. Recent development in NMDA receptors. Chin Med J (Engl). 2000 Oct;113(10):948-56. Review. PMID: [4]

glutamate receptor epsilon-4; N-methyl D-aspartate receptor subtype 2D; NMDAR2D; NR2D; EB11 (GRIN2D, NMDAR2D)