Glioma Pathogenesis Related Protein
From Anvita Health Wiki
Contents |
Structure
- belongs to the CRISP family
Compartment
- membrane ( potential)
Expression
- ubiquitously expressed with high levels in lung & kidney & low levels in heart & liver [3]
- highly expressed in cell lines derived from nervous system tumors arising from glia
- low or absent in non- glial-derived nervous system tumor cell lines
- also found in fetal kidney
- expressed only in brain tumor glioblastoma multiforme & astrocytoma & not in other nervous system tumors or normal fetal or adult tissues [4]
More General Terms
Internet Database
Entrez gene: 11010
Kegg: [1]
OMIM: 602692
Prosite: [2]
Prosite: [3]
UniProt: [4]
References
- UniProt [5]
- Entrez Gene [6]
- Rich T et al RTVP-1, a novel human gene with sequence similarity to genes of diverse species, is expressed in tumor cell lines of glial but not neuronal origin. Gene. 1996 Nov 21;180(1-2):125-30. PMID: [7]
- Murphy EV et al The human glioma pathogenesis-related protein is structurally related to plant pathogenesis-related proteins and its gene is expressed specifically in brain tumors. Gene. 1995 Jun 14;159(1):131-5. PMID: [8]
