General Receptor For Phosphoinositides 1 Associated Scaffold Protein

From Anvita Health Wiki

Contents 1 Function 2 Structure 3 Compartment 4 Alternative-splicing 5 More General Terms 6 Internet Database 7 References

Function

• role in intracellular trafficking
• role in macromolecular organization of group 1 metabotropic glutamate receptors at synapses
• interacts with PSCD3, GRM2, GRM3, GRM5
• component of heteromer composed of GRASP, PSCD2 & at least one GRM1

Structure

• contains 1 PDZ domain ( DHR domain)

Compartment

• cytoplasm, perinuclear region
• cell membrane, cytoplasmic side
• cell junction, synapse, postsynaptic cell membrane
• localized at postsynaptic membranes

Alternative-splicing

• named isoforms=2

More General Terms

• scaffold protein
• phosphoprotein
• membrane protein

Internet Database

Prosite: [1]
UniProt: [2]

References

UniProt [3]

general receptor for phosphoinositides 1-associated scaffold protein (GRP1-associated scaffold protein, GRASP)