Gefitinib

From Anvita Health Wiki

Contents 1 Introduction 2 Indications 3 Dosage 4 Mechanism-of-action 5 More General Terms 6 Internet Database 7 References

Introduction

• Tradname: Iressa ( FDA approved 2003)

Indications

• refractory lung cancer (about 10% of tumors shrink in size)

Dosage

• oral agent

Mechanism-of-action

• tyrosine kinase inhibitor

• inhibits epidermal growth factor receptor

More General Terms

• antineoplastic agent (chemotherapeutic agent)
• protein kinase inhibitor

Internet Database

PubChem: 123631

References

1. Prescriber's Letter 10(6):35 2003
2. National Guideline Clearinghouse
   - Gefitinib for the first-line treatment of locally advanced or metastatic non-small-cell lung cancer. National Institute for Health and Clinical Excellence (NICE) ngc-guideline: [1]

gefitinib (Iressa)