Formoterol

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Contents 1 More Specific Terms 2 Introduction 3 Indications 4 Contraindications 5 Dosage 6 Pharmacokinetics 7 Mechanism-of-action 8 Notes 9 More General Terms 10 Internet Database 11 References

More Specific Terms

• arformoterol (Brovana, R-formoterol)

Introduction

• Tradename: Foradil, Perforomist

Indications

• prevention of bronchospasm in patients with COPD

Contraindications

• NOT for treating symptoms of acute asthma (use albuterol)
• not for use in treating asthma without an inhaled glucocorticoid [14]

Dosage

• 2 puffs BID (9 mg/day)
• 2 puffs 15 minutes prior to exercise

• Performist: for nebulizer [3]

Pharmacokinetics

• similar onset of action to albuterol, faster than salmeterol

Mechanism-of-action

• selective beta-2 agonist

Notes

• Manufacturer: Novartis

More General Terms

• beta-2 adrenergic receptor agonist
• antiasthmatic agent

Internet Database

PubChem: 3083544
PubChem: 3410
PubChem: 104908
PubChem: 5282416

References

1. Prescriber's Letter 8(4):22 2001
2. Prescriber's Letter 9(2):S1 2002
3. Prescriber's Letter 14(6): 2007 Long-acting Beta-2 Agonists for Nebulization Detail-Document#: [1] (subscription needed) [2]
4. FDA advisory panel meeting Joint Meeting of the Pulmonary-Allergy Drugs Advisory Committee, Drug Safety & Risk Management Advisory Committee, and the Pediatric Advisory Committee December 10 & 11, 2008 [3]

formoterol (Foradil, Perforomist)