Ezogabine

From Anvita Health Wiki

Contents 1 Introduction 2 Indications 3 Adverse-effects 4 Mechanism-of-action 5 More General Terms 6 Internet Database 7 References

Introduction

• FDA approved June 2011

Indications

• adjunctive treatment of partial seizures

Adverse-effects

• urinary retention
• may increase risk of suicidal ideation
• dizziness
• diplopia
• memory impairment
• fatigue
  
• drug adverse effects of anticonvulsants

Mechanism-of-action

• facilitates opening of potassium channels

More General Terms

• anticonvulsant

Internet Database

PubChem: 121892

References

1. FDA NEWS RELEASE: June 13, 2011 FDA approves Potiga to treat seizures in adults [1]
2. French JA et al. on behalf of the RESTORE 1/Study 301 Investigators. Randomized, double-blind, placebo-controlled trial of ezogabine (retigabine) in partial epilepsy. Neurology 2011 Mar 30 [2]

ezogabine (Potiga, retigabine)