Egfr Coamplified & Overexpressed Protein

From Anvita Health Wiki

Contents 1 Function 2 Structure 3 Compartment 4 More General Terms 5 Internet Database 6 References

Function

• increases the transcriptional activity of NFKB1 by facilitating its nuclear translocation, DNA-binding & associated apoptotic response, when overexpressed

Structure

• belongs to the ECOP family

Compartment

• nucleus, membrane
• when overexpressed, localizes in the nucleus & perinuclear regions

More General Terms

• nuclear protein
• membrane protein

Internet Database

Kegg: [1]
Kegg: [2]
UniProt: [3]

References

UniProt [4]

EGFR-coamplified & overexpressed protein (ECop, Glioblastoma-amplified secreted protein, NF-kappa-B-activating protein 055N, ECOP, GASP)