Dna Damage Inducible Transcript 4 Like Protein

From Anvita Health Wiki

Contents 1 Function 2 Structure 3 Compartment 4 Expression 5 More General Terms 6 Internet Database 7 References

Function

• inhibits cell growth by regulating the FRAP1 pathway
• upstream of the TSC1- TSC2 complex & downstream of AKT1

Structure

• belongs to the DDIT4 family

Compartment

• cytoplasm ( putative)

Expression

• up-regulated in atherosclerotic plaques relative to healthy segments of the same artery
• up-regulated by oxidized LDL & hypoxia in macrophages

More General Terms

• uncharacterized protein

Internet Database

OMIM: 607730
UniProt: [1]

References

UniProt [2]

DNA-damage-inducible transcript 4-like protein (protein regulated in development & DNA damage response 2, REDD-2, HIF-1 responsive protein RTP801-like, DDIT4L, REDD2 RTP801L)