Developmental Pluripotency Associated 5 Protein

From Anvita Health Wiki

Contents 1 Function 2 Structure 3 Compartment 4 Expression 5 More General Terms 6 Internet Database 7 References

Function

• role in the maintenance of embryonic stem (ES) cells pluripotency
• dispensable for self-renewal of pluripotency ES cells & establishment of germ cells
• associates with specific target mRNAs ( putative)

Structure

• contains 1 KH domain

Compartment

• cytoplasm ( putative)

Expression

• expressed in primordial germ ( PGC), embryonic germ (EGC) & embryonic stem () cells
• not detected in embryonic <A21164>carcinoma</A21164> (ECC) cells
• down-regulated in <A4385>differentiated</A4385> <A19259>embryonic stem cells</A19259> (), compared with strong expression in undifferentiated cells

More General Terms

• uncharacterized protein

Internet Database

Prosite: [1]
UniProt: [2]

References

UniProt [3]

developmental pluripotency-associated 5 protein (hDPPA5, embryonal stem cell-specific gene 1 protein, Esg-1, DPPA5, ESG1)