Death
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More Specific Terms
Introduction
- Irreversible cessation of all biologic function.
Etiology
- In 2002, cancer surpassed heart disease as major cause of death for people under age 85. In 2002, 476,009 people died of cancer, 450,637 died of heart disease.
- Causes of death in the United States 2008 [7]
* heart disease 20.3% * cancer 18.6% * Lung cancer 5.2% * Leukemia//lymphoma 1.8% * Colorectal carcinoma 1.8% * Breast cancer 1.4% (both sexes combined) * pancreatic cancer 0.6% * prostate cancer 0.5% * chronic lung disease 4.6% * stroke 4.4% * accidents 4.0% motor vehicle 1.3% other 2.7% * Alzheimer's disease 2.7% * diabetes mellitus 2.3% * influenza & pneumonia 1.8% * renal failure 1.6% * sepsis 1.2% * suicide 1.2% * liver disease 1.0% * hypertension 0.8% * Parkinson's disease 0.7% * homicide 0.6% * all other causes 15.4% * Age 65 & over * heart disease 27.6% * cancer 21.8% * chronic lung disease 6.7% * stroke 6.3% * Alzheimer's disease 4.5% * diabetes mellitus 2.8% * influenza & pneumonia 2.7% * renal failure 2.2% * accidents 2.2% * sepsis 1.5% * all other causes 21.6%
- Until age 45, the most common cause of death is accidents [7]
- Until age 25, the most common cause of accident-related death is due to motor vehicle accidents [7]
- Age 45-64 cancer is the the most common cause of death, followed by heart disease & accidents [7]
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Epidemiology
- 64% of deaths < 65 years of age occur in males
- male/female ratio of deaths > 65 years of age ~= 1/1.
- 70% of deaths occur in individuals > 65 years of age
Clinical-manifestations
- cessation of respirations
- cessation of heartbeat
- patient is motionless
- patient cannot be aroused
- reflexes are absent (including corneal reflex)
- mouth may fall open as the jaw relaxes
- pupils are fixed & dilated
- eyelids may be partially open with eyes in a fixed stare
- any waste matter in the bowel or rectum will be released as the sphincter muscles relax
More General Terms
Additional Terms
References
- Medical Knowledge Self Assessment Program (MKSAP) 11, American College of Physicians, Philadelphia 1998
- Harrison's Principles of Internal Medicine, 14th ed. Fauci et al (eds), McGraw-Hill Inc. NY, 1998, pg 222
- Harrison's Principles of Internal Medicine, 13th ed. Isselbacher et al (eds), McGraw-Hill Inc. NY, 1994, pg 1106
- Netscape sites American Cancer Society [1]
- Death and Dying NIH Institute and Center Resources [2]
- National Guideline Clearinghouse Death of a child in the emergency department: joint statement by the American Academy of Pediatrics and the American College of Emergency Physicians. ngc-guideline: [3]
- Minino AM et al Deaths: Preliminary Data for 2008 National Vital Statistics Reports 59(2) 2010 Centers for Disease Control and Prevention (CDC) [4]
- Murphy SL et al Deaths: Preliminary Data for 2010 National Vital Statistics Reports 60(4) 2012 Centers for Disease Control and Prevention (CDC) [5]
- National Center for Health Statistics [6]
