D Glucuronyl C5 Epimerase

From Anvita Health Wiki

Contents 1 Function 2 Structure 3 Compartment 4 More General Terms 5 Internet Database 6 References

Function

• converts D- glucuronic acid residues adjacent to N-sulfate sugar residues to L- iduronic acids
• heparin & heparan sulfate biosynthesis
• interacts with HS2ST1

Structure

• belongs to the D-glucuronyl C5- epimerase family

Compartment

• Golgi
• single-pass type 2 membrane protein ( putative)

More General Terms

• epimerase
• membrane protein
• phosphoprotein

Internet Database

Entrez gene: 26035
Kegg: [1]
UniProt: [2]

References

UniProt [3]

D-glucuronyl C5-epimerase; heparin/heparan sulfate:glucuronic acid C5-epimerase (GLCE, KIAA0836)