Cytochrome P450 51a1

From Anvita Health Wiki

Contents 1 Function 2 Structure 3 Compartment 4 Expression 5 More General Terms 6 Internet Database 7 References

Function

• involved in cholesterol biosynthesis
• catalyzes C14- demethylation of lanosterol
• transforms lanosterol into 4,4'-dimethyl cholesta-8,14,24- triene-3-beta-ol

Structure

• belongs to the cytochrome P450 family

Compartment

• microsome ( putative)

Expression

• ubiquitously expressed
• highest levels in testis, ovary, adrenal, prostrate, liver, kidney & lung

More General Terms

• cytochrome P450
• membrane protein
• demethylase

Internet Database

OMIM: 601637
Kegg: [1]
Prosite: [2]
UniProt: [3]
Entrez gene: 1595

References

UniProt [4]

cytochrome P450 51; sterol 14-alpha demethylase; lanosterol 14-alpha demethylase (CYPL1, P450L1, LDM, P450-14DM)