Cytochrome B5

From Anvita Health Wiki

Contents 1 More Specific Terms 2 Function 3 Structure 4 Compartment 5 Alternative-splicing 6 Pathology 7 More General Terms 8 Internet Database 9 References

More Specific Terms

• cytochrome b5 type B; cytochrome b5 outer mitochondrial membrane isoform (CYB5B, CYB5M, OMB5)

Function

• membrane bound hemoprotein
• electron carrier for several membrane bound oxygenases

Structure

• belongs to the cytochrome b5 family
• contains 1 cytochrome b5 heme-binding domain

Compartment

• isoform 1: endoplasmic reticulum membrane, cytoplasmic side
• isoform 2: cytoplasm

Alternative-splicing

• named isoforms=2

Pathology

• defects in CYB5A are the cause of hereditary methemoglobinemia type 4 [MIM:250790]

More General Terms

• cytochrome
• membrane protein

Internet Database

Kegg: [1]
OMIM: 250790
Prosite: [2]
Prosite: [3]
UniProt: [4]

References

UniProt [5]

cytochrome b5 (CYB5A, CYB5)