Connexin

From Anvita Health Wiki

Contents 1 More Specific Terms 2 Function 3 Structure 4 More General Terms 5 Internet Database 6 References

More Specific Terms

• connexin-25 (connexin-25, Cx25, GJB7, CX25)
• connexin-26 (CX26, gap junction protein beta-2, GJB2)
• connexin-30 (CX30) or gap junction protein beta-6
• connexin-30.3 (CX30.3) or gap junction protein beta-4
• connexin-31 (CX31) or gap junction protein beta-3
• connexin-31.1 (CX31.1) or gap junction protein beta-5
• connexin-32 (CX32) or gap junction protein beta-1
• connexin-36 (CX36) or gap junction protein alpha-9 (GJA9)
• connexin-37 (CX37) or gap junction protein alpha-4
• connexin-40 (CX40) or gap junction protein alpha-5
• connexin-43 (CX43) or gap junction protein alpha-1
• connexin-45 (CX45) or gap junction protein alpha-6
• connexin-46 (CX46) or gap junction protein alpha-3 (GJA3)
• connexin-47 (gap junction alpha-12 protein, Cx47, connexin-46.6, Cx46.6, GJA12)
• connexin-50 (CX50) or gap junction protein alpha-8
• gap junction alpha-10 protein (connexin-62, Cx62, GJA10 CX62)
• gap junction alpha-9 protein (connexin-59, Cx59, connexin-58, Cx58, GJA9, GJA10)
• gap junction delta-3 protein (gap junction chi-1 protein, gap junction alpha-11 protein, connexin 31.9, Cx31.9, GJD3, GJA11, GJC1)
• connexin-23 (gap junction epsilon-1 protein, Cx23, GJE1)
• connexin-31.3 gap junction gamma-3 protein, gap junction epsilon-1 protein, Cx31.3, GJC3, GJE1)

Function

• Ca+2/ calmodulin & Tyr phosphorylation may mediate gap junction closure

Structure

• two hexamers in plasma membranes of juxtaposed cells form a gap junction

More General Terms

• transmembrane 4 protein
• oligomerizing protein
• channel
• plasma membrane protein
• PEST protein
• calmodulin binding protein

Internet Database

Prosite: [1]
Prosite: [2]

References

1. Molecular Cell Biology (2nd ed) Darnell J; Lodish H & Baltimore D (eds), Scientific American Books, WH Freeman, NY 1990, pg 525
2. Bishop JM. Molecular themes in oncogenesis. Cell. 1991 Jan 25;64(2):235-48. Review. No abstract available. PMID: [3]
3. Wang KK et al Calmodulin-binding proteins as calpain substrates. Biochem J 262:693 1989 PMID: [4]
4. Lo Turco JJ, Kriegstein AR. (conductance) Clusters of coupled neuroblasts in embryonic neocortex. Science. 1991 Apr 26;252(5005):563-6. PMID: [5]

connexin (gap-junction protein)