Coiled Coil Domain Containing Protein 136

From Anvita Health Wiki

Contents 1 Structure 2 Compartment 3 Alternative-splicing 4 Expression 5 Notes 6 More General Terms 7 Internet Database 8 References

Structure

• contains 2 LRR repeats ( leucine-rich repeats)

Compartment

• membrane ( putative)

Alternative-splicing

• named isoforms=4

Expression

• expressed in gastric tissues
• down-regulated in gastric cancer

Notes

• restriction fragment length polymorphisms ( RFLPs) in gastric cancer showed loss of 5 kb fragment in comparison with the corresponding normal tissue

More General Terms

• membrane protein

Internet Database

UniProt: [1]

References

UniProt [2]

coiled-coil domain-containing protein 136 (nasopharyngeal carcinoma-associated gene 6 protein, CCDC136, KIAA1793, NAG6)