Cenp E
From Anvita Health Wiki
Contents |
Function
- minus-end directed microtubule motor
- probable kinetochore motor
- accumulates just before mitosis at the G2 phase of the cell cycle
- probably important for chromosome movement &/or spindle elongation
- interacts with CENP-F, BUBR1 kinase & PRC1
Structure
- belongs to the kinesin-like protein family
- contains 1 kinesin-motor domain
Compartment
- kinetochore, spindle, centromere
- associates with kinetochores during congression
- relocates to the spindle midzone at anaphase
- quantitatively discarded at the end of cell division
Alternative-splicing
- named isoforms=3
More General Terms
Internet Database
UniProt: [1]
Kegg: [2]
OMIM: 117143
Prosite: [3]
Prosite: [4]
References
UniProt [5]
