Cell Surface A33 Antigen

From Anvita Health Wiki

Contents 1 Function 2 Structure 3 Compartment 4 Expression 5 Pathology 6 More General Terms 7 Additional Terms 8 Internet Database 9 References

Function

• role in cell-cell recognition & signaling

Structure

• N-glycosylated, contains approximately 8 kD of N-linked carbohydrate
• palmitoylated
• contains 1 Ig-like C2-type domain ( immunoglobulin-like)
• contains 1 Ig-like V-type domain ( immunoglobulin-like)

Compartment

• membrane

Expression

• expressed in normal gastrointestinal epithelium

Pathology

• expressed in 95% of colon cancers (but also expressed in normal gastrointestinal epithelium)

More General Terms

• glycoprotein
• membrane protein

Additional Terms

• V-set & immunoglobulin domain-containing protein 1; cell surface A33 antigen; glycoprotein A34 (VSIG1, GPA34)

Internet Database

OMIM: 602171
UniProt: [1]

References

UniProt [2]

cell surface A33 antigen (glycoprotein A33, GPA33)