Cell Cycle Progression Protein 1

From Anvita Health Wiki

Contents 1 Function 2 Structure 3 Compartment 4 Alternative-splicing 5 More General Terms 6 Internet Database 7 References

Function

• acts as an assembly platform for Rho protein signaling complexes
• limits guanine nucleotide exchange activity of MCF2L toward RHOA, which results in an inhibition of both its transcriptional activation ability & its transforming activity
• does not inhibit activity of MCF2L toward CDC42, or activity of MCF2 toward either RHOA or CDC42 ( putative)
• may be involved in cell cycle regulation
• interacts with MCF2L
• may interact with MCF2, ARHGEF1, BCR, VAV1 & FGD1, but not with TIAM1
• interacts with GTP-bound CDC42 & SRC ( putative)

Structure

• belongs to the CCPG1 family

Compartment

• cytoplasmic granule membrane

Alternative-splicing

• named isoforms=4

More General Terms

• phosphoprotein
• membrane protein

Internet Database

UniProt: [1]

References

UniProt [2]

cell cycle progression protein 1 (cell cycle progression restoration protein 8, CCPG1, CCP8, CPR8, KIAA1254)