Cdgsh Iron Sulfur Domain Containing Protein 2

From Anvita Health Wiki

Contents 1 Function 2 Structure 3 Compartment 4 Expression 5 Pathology 6 More General Terms 7 Internet Database 8 References

Function

• may play a role in Ca+2 homeostasis

• Cofactor: binds 1 2Fe-2S cluster

Structure

• belongs to the CISD protein family

Compartment

• endoplasmic reticulum membrane

Expression

• testis, small intestine, kidney, lung, brain, pancreas & platelets

Pathology

• defects in CISD2 are the cause of Wolfram syndrome 2

More General Terms

• membrane protein

Internet Database

Kegg: [1]
OMIM: 604928
UniProt: [2]

References

UniProt [3]

CDGSH iron sulfur domain-containing protein 2 (endoplasmic reticulum intermembrane small protein, mitoNEET-related 1 protein, Miner1, CISD2, ERIS, ZCD2)