Cd99 Antigen Like Protein 2

From Anvita Health Wiki

Contents 1 Function 2 Structure 3 Compartment 4 Alternative-splicing 5 Expression 6 More General Terms 7 Internet Database 8 References

Function

• may function as a homophilic adhesion molecule
• functions in leukocyte- endothelial cell interactions during leukocyte extravasation, & in particular, at the diapedesis step
• does not seem to be involved in docking of leukocytes to the vessel wall or in lymphocyte diapedesis ( putative)
• O-glycosylated ( putative)

Structure

• belongs to the CD99 family

Compartment

• cell membrane, extracellular side
• cell junction

Alternative-splicing

• named isoforms=4

Expression

• expressed in brain, heart, lung, liver, spleen, kidney, stomach, small intestine, skeletal muscle, ovary, thymus, testis & uterus. lower expression seen in thymus
• expressed in E18 uterus & placenta

More General Terms

• membrane protein
• adhesion protein

Internet Database

Kegg: [1]
UniProt: [2]

References

UniProt [3]

CD99 antigen-like protein 2 (MIC2-like protein 1, CD99L2, MIC2L1, UNQ1964/PRO4486)