Cd39

From Anvita Health Wiki

Contents 1 Function 2 Structure 3 Compartment 4 Alternative-splicing 5 Expression 6 More General Terms 7 Additional Terms 8 Internet Database 9 References

Function

• inhibitor of platelet activation
• in the nervous system, may hydrolyze ATP & other nucleotides to regulate purinergic neurotransmission
• hydrolyzes ATP & ADP equally well
  

• Cofactor: Ca+2, Mg+2

Structure

• homodimer, disulfide-linked ( putative)
• the N-terminus is blocked
• palmitoylated in the N-terminal part
• belongs to the GDA1/CD39 NTPase family

Compartment

• membrane ( putative)

Alternative-splicing

• named isoforms=3

Expression

• B cells, T cells, NK cells
• endothelial cells
• placenta

More General Terms

• CD antigen
• adenosine triphosphatase (ATPase)
• pyrophosphatase (diphosphohydrolase)
• glycoprotein
• membrane protein

Additional Terms

• CD39 like protein (CD39 like antigen, CD39L, ectonucleoside triphosphate diphosphohydrolase)

Internet Database

Kegg: [1]
OMIM: 601752
Prosite: [2]
UniProt: [3]

References

1. url>http://www.pathologyoutlines.com/cdmarkers.html</url> 15 October 2002
2. UniProt [4]

CD39; ectonucleoside triphosphate diphosphohydrolase 1; NTPDase 1; ecto-ATP diphosphohydrolase; ATPDase; lymphoid cell activation antigen; ecto-apyrase (ENTPD1)