Cardiac Tamponade
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Contents |
Introduction
- Heart failure secondary to compression of cardiac chambers by fluid within the pericardial space.
Etiology
- pericarditis of any cause
- viral & neoplastic forms of pericarditis most common
Epidemiology
- slightly more common in men than women [4] Pathophysiology
- accumulation of fluid within the pericardial space
- increased intrapericardial pressure
- as little as 30 mL in the pericardial sac can cause pericardial tamponade
Clinical-manifestations
- abrupt onset
- dyspnea, orthopnea
- elevation of central venous & jugular venous pressure
- hepatic engorgement
- hypotension
- narrow pulse pressure
- pulsus paradoxus is common
- sinus tachycardia
- evidence of poor peripheral perfusion
- distant heart sounds
- pulseless electrical activity
Laboratory
- serum tropnonin I
- cardiac-specific troponin-I, elevated in patients with myocardial infarction & cardiac trauma
- serum creatinine/ serum urea nitrogen to assess for uremia
- complete blood count ( CBC)
- coagulation panel: assess bleeding risk
- antinuclear antibody assay, erythrocyte sedimentation rate, & rheumatoid factor: nonspecific, but may suggest connective tissue disease as predisposing factor
- HIV testing: 24% of all pericardial effusions may be associated with HIV infection.
- PPD testing: rule out tuberculosis Special Laboratory:
- electrocardiogram ( EKG)
- no thickened pericardium
- no pericardial calcifications
- pericardial effusion
- right ventricular size generally small
- myocardial thickness generally normal
- right atrial & right ventricular diastolic collapse
- increased right-sided flow during inspiration
- respiratory variation of trans-mitral flow
- right heart catheterization
- elevated, atrial/ventricular equalized diastolic pressure
Radiology
- chest X-ray may show cardiomegaly, water bottle-shaped heart, pericardial calcifications, or evidence of chest wall trauma Differental diagnosis:
- cardiogenic shock
- constrictive pericarditis
- pulmonary embolism
- tension pneumothorax [4]
Management
-
- ECG &/or echocardiographic guidance
- blood from pericardium does not clot
- supportive prior to definitive therapy
- inotropic agents
- aggressive administration of IV saline to maintain adequate ventricular filling
- preload- reducing agents are *absolutely contraindicated*
- mechanical ventilation exacerbates hemodynamic compromise; avoid if possible [2]
- surgical pericardiotomy
- may be done with videothorascopic guidance
- percutaneous balloon pericardiotomy for patients who as poor surgical candidates
- subacute cardiac tamponade with mild hemodynamic compromise may be managed conservatively
- serial hemodynamic monitoring
- serial echocardiography
- mananagement of volume status
- treatment of causative disorder [2]
More General Terms
Additional Terms
References
- Manual of Medical Therapeutics, 28th ed, Ewald & McKenzie (eds), Little, Brown & Co, Boston, 1995, pg 135
- Medical Knowledge Self Assessment Program (MKSAP) 11, 14, 15 American College of Physicians, Philadelphia 1998, 2006, 2009
- Harrison's Principles of Internal Medicine, 13th ed. Isselbacher et al (eds), McGraw-Hill Inc. NY, 1994, pg 1097
- eMedicine: Cardiac Tamponade [1]
