C Type Lectin Like Domain Family 1

From Anvita Health Wiki

Contents 1 Function 2 Structure 3 Compartment 4 Expression 5 More General Terms 6 Internet Database 7 References

Function

• may function in mediating immune cell-cell interactions
• may act as a T-cell costimulatory molecule, enhancing anti- CD3-induced proliferation
• may play a role in the interaction of dendritic cells with T-cells & the cells of the adaptive immune response

Structure

• contains 1 C-type lectin domain

Compartment

• cell membrane

Expression

• expressed in spleen, lymph node, & tonsil
• lower expression in peripheral blood, bone marrow, & colon
• no expression detected in thymus
• highly expressed in dendritic & B-cells

More General Terms

• glycoprotein
• membrane protein
• C-type lectin superfamily

Internet Database

Kegg: [1]
OMIM: 607467
Prosite: [2]
UniProt: [3]

References

UniProt [4]

C-type lectin-like domain family 1 (dendritic cell-associated lectin 1, DC-associated lectin-1, DCAL-1, CLECL1, DCAL1)