Bmp & Activin Membrane Bound Inhibitor Homolog

From Anvita Health Wiki

Contents 1 Function 2 Compartment 3 Expression 4 Pathology 5 More General Terms 6 Internet Database 7 References

Function

• negatively regulates TGF-beta signaling

Compartment

• membrane

Expression

• expressed in in renal medulla, placenta, spleen > renal cortex, liver, prostate, gut
• Not expressed in normal skin
• expression is high in melanocytes

Pathology

• diminished or no expression in metastatic melanoma

More General Terms

• membrane protein
• glycoprotein

Internet Database

OMIM: 604444
UniProt: [1]

References

UniProt [2]

BMP & activin membrane-bound inhibitor homolog (transmembrane protein NMA, non-metastatic gene A protein, BAMBI, NMA)