Bleeding Time

From Anvita Health Wiki

Contents 1 More Specific Terms 2 Reference-interval 3 Increases 4 More General Terms 5 Additional Terms 6 References

More Specific Terms

• bleeding time Duke
• bleeding time Ivy

Reference-interval

• Ivy: 2-7 minutes (7-11 minutes is borderline)
• Simplate* ( template): 2.5-9.5 minutes
• Mielke ( template): < 10 minutes
• Mielke (modified): 2.8 +/- 1.6 minutes
• Duke ( ear lobe): 1-3 minutes
  

• * (method of choice)

Increases

• (prolonged bleeding time)
• thrombocytopenia ( platelets < 60,000-80,000/ uL)
• Glanzmann's thrombasthenia
• von Willebrand's disease
• Bernard-Soulier syndrome
• disseminated intravascular coagulation ( DIC)
• storage pool disease
• Wiskott-Aldrich syndrome
• Chediak-Higashi syndrome
• oculocutaneous albinims
• hereditary hemorrhagic telangiectasias
• Ehlers-Danlos syndrome
• myeloproliferative disorders
• multiple myeloma & Waldenstrom's macroglobulinemia
• vasculitis
• uremia
• drugs

• anti-platelet agents
• non-steroidal anti-inflammatory agents
• heparin may be associated with increased bleeding time
• tricyclic antidepressants
• high-dose beta-lactam antibiotics
• phenothiazines
• methylxanthines

More General Terms

• clinical hematology test

Additional Terms

• Bernard-Soulier disease (giant platelet syndrome, benign Mediterranean macrothrombocytopenia)
• disseminated intravascular coagulation (DIC)
• Glanzmann's thrombasthenia
• storage pool disease
• thrombocytopenia
• uremia
• von-Willebrand's disease (vWD)

References

1. Mayo Internal Medicine Board Review, 1998-99, Prakash UBS (ed) Lippincott-Raven, Philadelphia, 1998, pg 437-38
2. Clinical Guide to Laboratory Tests, 3rd edition, NW Tietz ed, WB Saunders, Philadelphia, 1995
   - Henry's Clinical Diagnosis & Management by Laboratory Methods, 21st edition, McPherson RA & Pincus MR (es), W.B. Saunders Co., Philadelphia, PA. 2007
3. Interpretation of Diagnostic tests, 8th edition, Wallach J, Lippincott, Williams & Wilkens, Philadelphia, 2007, pg 520

bleeding time