Beta 1 4 N Acetylgalactosaminyltransferase 2

From Anvita Health Wiki

Contents 1 Function 2 Structure 3 Compartment 4 Alternative-splicing 5 Expression 6 More General Terms 7 Internet Database 8 References

Function

• glycosylation

• role in synthesis of the Sd(a) antigen
• transfers a beta-1,4-linked GalNAc to the galactose residue of an alpha-2,3-sialylated chain

Structure

• belongs to the glycosyltransferase 2 family

Compartment

• Golgi membrane

Alternative-splicing

• named isoforms=2

Expression

• widely expressed
• expressed in colon > kidney, stomach, ileum & rectum

More General Terms

• beta-1,4-N-acetylgalactosaminyltransferase (B4GALNT)
• glycoprotein
• membrane protein

Internet Database

UniProt: [1]

References

1. UniProt [2]
2. GlycoGene database [3]

beta-1,4 N-acetylgalactosaminyltransferase 2 (Sd(a) beta-1,4-GalNAc transferase, UDP-GalNAc:Neu5Aca2-3Galb-R b1,4-N-acetylgalactosaminyltransferase, B4GALNT2, GALGT2)