Beta 1 2 N Acetylglucosaminyltransferase 2

From Anvita Health Wiki

Contents 1 Function 2 Compartment 3 Pathology 4 More General Terms 5 Internet Database 6 References

Function

• catalyzes an essential step in the conversion of oligo- mannose to complex N-glycans
• protein modification; protein glycosylation

Compartment

• Golgi membrane
• single-pass type 2 membrane protein

Pathology

• defects in MGAT2 are the cause of congenital disorder of glycosylation type 2A

More General Terms

• aminotransferase
• glycoprotein
• membrane protein

Internet Database

Entrez gene: 4247
Kegg: [1]
OMIM: 212066
OMIM: 602616
UniProt: [2]

References

1. UniProt [3]
2. GeneReviews [4]
3. GGDB; Note: glycogene database [5]
4. Functional glycomics gateway - GTase alpha-1,6-mannosyl-glycoprotein 2-beta-N-acetylglucosaminyl- transferase [6]

alpha-1,6-mannosyl-glycoprotein 2-beta-N-acetylglucosaminyltransferase; beta-1,2-N-acetylglucosaminyltransferase II; GlcNAc-T II; GNT-II; mannoside acetylglucosaminyltransferase 2; N-glycosyl-oligosaccharide-glycoprotein N-acetylglucosaminyltransferase II (MGAT2)