Berylliosis

From Anvita Health Wiki

Contents 1 Etiology 2 Epidemiology 3 Pathology 4 Clinical-manifestations 5 Laboratory 6 Radiology 7 Differential-diagnosis 8 Management 9 More General Terms 10 Additional Terms 11 References

Etiology

• acute beryllium exposure by inhalation
• chronic beryllium exposure

Epidemiology

• ceramic workers
• beryllium processors
• some aerospace workers
• workers in light bulb or semiconductor factories [2]

Pathology

• acute berylliosis

• tracheobronchitis
• chemical pneumonitis

• chronic berylliosis

• delayed-type hypersensitivity reaction
• sarcoid-like granulomatous disease

Clinical-manifestations

• resembles sarcoidosis

Laboratory

• beryllium lymphocyte transformation test

Radiology

• resembles sarcoidosis
• chest X-ray:

• predominantly upper lobe interstitial infiltrates

Differential-diagnosis

• sarcoidosis

Management

• corticosteroids for symptomatic patients

More General Terms

• occupational lung disease
• granulomatous disease
• toxicity; poisoning; overdose

Additional Terms

• beryllium [Be]
• sarcoidosis

References

1. Mayo Internal Medicine Board Review, 1998-99, Prakash UBS (ed) Lippincott-Raven, Philadelphia, 1998, pg 759
2. Medical Knowledge Self Assessment Program (MKSAP) 14, American College of Physicians, Philadelphia 2006

berylliosis