Autosomal Dominant

From Anvita Health Wiki

Introduction

• A mode of inheritance from autosomes in which inheritance of a single allele for the trait is sufficient for phenotypic manifestation of the trait. The classic example is brown eyes.

• Of interest, is the types of mutations that manifest as disease that is inherited in an autosomal dominant pattern.
• These include:

• gain of function mutations (overactivity of an enzyme)

More General Terms

• mode of inheritance

autosomal dominant