Armadillo Repeat Containing Protein 10

From Anvita Health Wiki

Contents 1 Function 2 Structure 3 Compartment 4 Alternative-splicing 5 Expression 6 Pathology 7 More General Terms 8 Internet Database 9 References

Function

• role in cell survival & cell growth ( putative)

Structure

• contains 1 ARM repeat

Compartment

• endoplasmic reticulum membrane

Alternative-splicing

• named isoforms=4

Expression

• expressed in all tissues tested
• higher expression in placenta, liver, kidney, heart & brain

Pathology

• depletion of isoform 2 results in cell apoptosis
• overexpression of isoform 2 leads to accelerated growth rate & tumorogenicity

More General Terms

• armadillo repeat-containing X-linked protein
• glycoprotein
• membrane protein
• phosphoprotein

Internet Database

Prosite: [1]
UniProt: [2]

References

UniProt [3]

armadillo repeat-containing protein 10 (splicing variant involved in hepatocarcinogenesis protein, ARMC10, SVH, PSEC0198)