Antiendomysial Antibody

From Anvita Health Wiki

Contents 1 More Specific Terms 2 Etiology 3 Reference-interval 4 Clinical-significance 5 Methods 6 Specimen 7 More General Terms 8 Additional Terms 9 References

More Specific Terms

• endomysial antibody IgA in serum

Etiology

• positive values present in 70-80% of patients with:

• celiac disease
• dermatitis herpetiformis

Reference-interval

• negative

Clinical-significance

• IgA antibody has sensitivity, specificity & positive predictive value of 95% for celiac sprue

Methods

• monkey esophagus is used as tissue substrate

Specimen

• serum; store at -20 degrees C

More General Terms

• serology

Additional Terms

• anti-gliadin antibody
• celiac sprue (gluten-sensitive enteropathy)
• endomysium

References

1. Medical Knowledge Self Assessment Program (MKSAP) 11, American College of Physicians, Philadelphia 1998
2. Clinical Guide to Laboratory Tests, 3rd ed. Teitz ed., W.B. Saunders, 1995

anti-endomysial antibody