Anticonvulsant
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Contents |
More Specific Terms
- amobarbital (Amytal)
- carbamazepine; CBZ (Tegretol, Atretol, Eiptol, Carbatrol, Equetro)
- clonazepam (Klonopin)
- diazepam (Vallium, Diastat)
- ethosuximide (Zarontin)
- ethotoin; 3-ethyl-5-phenyl-2,4-imidazolidinedione (Peganone)
- ezogabine (Potiga, retigabine)
- felbamate (Felbatol)
- fosphenytoin (Cerebyx)
- gabapentin (Neurontin, Gralise)
- lacosamide (Vimpat, erlosamide, harkoseride)
- lamotrigine (Lamictal, Lamictal ODT, Lamictal XR)
- levetiracetam (Keppra, Etiracetam)
- mephenytoin; methoin; methylphenylethylhydantoin (Mesantoin)
- methsuximide (Celontin, Kapseal)
- oxcarbazepine (Trileptal)
- phenobarbital; PB; PHB (Luminal, Barbita, Solfoton)
- phensuximide (Milontin)
- phenylethylmalonamide (PEMA)
- phenytoin; diphenylhydantoin; PTN (Dilantin, Dephenylan, Antilepsin)
- primidone; desoxyphenobarbital (Primaclone, Mysoline)
- rufinamide (Banzel, Inovelon, Xilep)
- tiagabine (Gabitril)
- topiramate (Topamax)
- trimethadione (Tridione)
- valproic acid; n-dipropylacetic acid (Depakene, Depakote, Divalproex, Mylproin, Valontin, Stavzor)
- vigabatrin (Sabril)
- zonisamide (Zonegran)
Introduction
- See specific agent
Indications
- prevention & treatment of seizures
Adverse-effects
- suicide, 2-fold risk of suicidal behavior or ideation compared to patients receiving placebo
- withdrawal effects with abrupt discontinuation [3]
More General Terms
References
- Prescriber's Letter 11(12): 2004 Comparison of FDA-Approved Antiepileptic Drugs Detail-Document#: [1] (subscription needed) [2]
- Prescriber's Letter 14(7): 2007 Generic Substitution of Antiepileptic Drugs Detail-Document#: [3] (subscription needed) [4]
- FDA News FDA Requires Warnings about Risk of Suicidal Thoughts and Behavior for Antiepileptic Medications Dec. 16, 2008 [5]
- National Guideline Clearinghouse Annual monitoring for patients on persistent medications: percentage of health plan members 18 years of age and older who received at least a 180-days supply of ambulatory medication therapy for anticonvulsants (phenytoin, phenobarbital, valproic acid, carbamazepine) during the measurement year and at least one drug serum concentration level monitoring test for the prescribed drug in the measurement year. National Committee for Quality Assurance ngc-guideline: [6]
