Anti Ri Antibody

From Anvita Health Wiki

Contents 1 Pathology 2 Laboratory 3 More General Terms 4 Additional Terms 5 References

Pathology

• cerebellar ataxia
• myelopathy
• opisthotonus-myoclonus

• paraneoplastic opsoclonus myoclonus

• other brain stem disorders
• associated malignancy

• breast cancer
• gynecologic cancer
• small cell lung carcinoma

Laboratory

• Antibody directed against 55 kD RNA-binding protein in motor system neurons.
• Neuronal antigen:

• CNS neuronal nuclei

• NOVA1
• NOVA2
• p55 & p80

More General Terms

• paraneoplastic autoantibody
• antineuronal nuclear antibody (ANNA)
• serology

Additional Terms

• neurooncologic ventral antigen-2 (NOVA-2, astrocytic NOVA-1 like protein, ANOVA)
• RNA-binding protein Nova-1; neuro-oncological ventral antigen 1; onconeural ventral antigen 1; paraneoplastic Ri antigen; ventral neuron-specific protein 1 (NOVA1)

References

1. Mayo Internal Medicine Board Review, 1998-99, Prakash UBS (ed) Lippincott-Raven, Philadelphia, 1998, pg 651
2. Harrison's Principles of Internal Medicine, 14th ed. Fauci et al (eds), McGraw-Hill Inc. NY, 1998, pg 625
3. Stuve O & Zamvil SS. In: Medical Immunology 10th edition (2001), Section 3, Clinical Immunology. 38. Neurologic diseases

anti-Ri antibody (type-2 ANNA)