Anti Mannan Antibody

From Anvita Health Wiki

Contents 1 Introduction 2 Etiology 3 Clinical-significance 4 More General Terms 5 References

Introduction

• Antibody to mannan.

Etiology

• Crohn's disease

Clinical-significance

• associated with Crohn's disease.
• in patients with inflammatory bowel disease, detection of 2 of 3 antibodies:

• anti-laminaribioside
• anti-chitobioside
• anti- mannan is 99% specific for Crohn's disease,

• higher titers of anti-laminaribioside or anti- mannan associated with small intestinal disease

More General Terms

• serology

References

1. Dotan I, Fishman S, Dgani Y, Schwartz M, Karban A, Lerner A, Weishauss O, Spector L, Shtevi A, Altstock RT, Dotan N, Halpern Z. Antibodies against laminaribioside and chitobioside are novel serologic markers in Crohn's disease. Gastroenterology. 2006 Aug;131(2):366-78. PMID: [1]

anti-mannan antibody