Ankyrin 3

From Anvita Health Wiki

Contents 1 Function 2 Structure 3 Compartment 4 Alternative-splicing 5 Expression 6 More General Terms 7 Internet Database 8 References

Function

• membrane- cytoskeleton linker
• the neural-specific isoforms may participate in maintenance &/or targeting of ion channels & cell adhesion molecules at the nodes of Ranvier & axonal initial segments
• neural-specific isoforms may be a constituent of a neurofascin/ NRCAM/ ankyrin G complex
• interacts with RHBG

Structure

• contains 23 ANK repeats
• contains 1 death domain
• contains 1 ZU5 domain

Compartment

• cytoplasm, cytoskeleton

Alternative-splicing

• named isoforms=2

Expression

• expressed in brain & other tissues
• isoform1 is neural-specific

More General Terms

• ankyrin

Internet Database

Entrez gene: 288
OMIM: 600465
Prosite: [1]
Prosite: [2]
Prosite: [3]
Prosite: [4]
UniProt: [5]

References

1. UniProt [6]
2. Wikipedia; Note: ankyrin entry [7]
3. OMIM [8]
4. Entrez Gene [9]

ankyrin-3; ANK-3; ankyrin-G (ANK3)