Anion Exchange Protein 3

From Anvita Health Wiki

Contents 1 Function 2 Structure 3 Compartment 4 Alternative-splicing 5 Expression 6 More General Terms 7 Internet Database 8 References

Function

• plasma membrane anion exchange protein of wide distribution
• mediates at least a part of the Cl-/ HCO3- exchange in cardiac myocytes
• both isoforms BAE3 & CAE3 transport Cl-

Structure

• belongs to the anion exchanger (TC 2.A.31) family

Compartment

• membrane

Alternative-splicing

• named isoforms=2, BAE3, CAE3

• Additional isoforms seem to exist

Expression

• both BAE3 & CAE3 isoforms are expressed in failing ventricle

More General Terms

• anion exchange protein
• Cl- channel
• plasma membrane protein
• glycoprotein
• solute carrier family 4 (SLC4, SLC4A)

Internet Database

OMIM: 106195
Prosite: [1]
Prosite: [2]
UniProt: [3]

References

UniProt [4]

anion exchange protein 3 (neuronal band 3-like protein, cardiac/brain band 3-like protein, CAE3/BAE3, solute carrier family 4 member 3, SLC4A3, SLC2, AE3)