Amiloride Sensitive Cation Channel 5

From Anvita Health Wiki

Contents 1 Function 2 Structure 3 Compartment 4 Expression 5 More General Terms 6 Internet Database 7 References

Function

• cation channel that gives rise to very low constitutive currents in the absence of activation
• the activated channel exhibits selectivity for Na+
• inhibited by amiloride

Structure

• homotetramer or heterotetramer ( putative)
• belongs to the amiloride-sensitive Na+ channel family

Compartment

• cell membrane

Expression

• detected in small intestine, duodenum & jejunum
• detected at very low levels in testis & rectum

More General Terms

• glycoprotein
• amiloride-sensitive cation channel

Internet Database

Kegg: [1]
Prosite: [2]
Entrez gene: 51802
UniProt: [3]

References

UniProt [4]

amiloride-sensitive cation channel 5 (human intestine Na+ channel, HINaC, ACCN5, HINAC)