Alpha Mannosidase 2x
From Anvita Health Wiki
Contents |
Function
- protein modification; protein glycosylation
- catalyzes the 1st committed step in the biosynthesis of complex N-glycans ( N-glycosylation)
- controls conversion of high mannose to complex N-glycans
- final hydrolytic step in the N-glycan maturation
Structure
- homodimer, disulfide-linked
- belongs to the glycosyl hydrolase 38 family
Compartment
- Golgi membrane
- single-pass type 2 membrane protein ( putative)
Alternative-splicing
- named isoforms=2
- at least one isoform may be produced at very low levels due to a premature stop codon in the mRNA, leading to nonsense-mediated mRNA decay
More General Terms
Additional Terms
Internet Database
Entrez gene: 4122
Kegg: [1]
OMIM: 600988
UniProt: [2]
References
UniProt [3]
