Alpha 1 4 N Acetylglucosaminyltransferase

From Anvita Health Wiki

Contents 1 Function 2 Structure 3 Compartment 4 Expression 5 More General Terms 6 Internet Database 7 References

Function

• glycosylation
• necessary for the synthesis of mucin type 3
• catalyzes transfer of N-acetylglucosamine ( GlcNAc) to core 2 branched O- glycans

Structure

• belongs to the alpha 1,4- glycosyltransferase family
• conserved DXD motif is involved in enzyme activity

Compartment

• Golgi membrane

Expression

• detected in stomach & pancreas

More General Terms

• glycosyltransferase
• membrane protein
• glycoprotein

Internet Database

Entrez gene: 51146
Kegg: [1]
UniProt: [2]

References

1. UniProt [3]
2. GGDB; Note: glycogene database [4]
3. Functional glycomics gateway - GTase alpha-1,4-N-acetylglucosaminyltransferase [5]

alpha-1,4-N-acetylglucosaminyltransferase (Alpha4GnT, A4GNT)