Aldosterone Antagonist

From Anvita Health Wiki

Contents 1 More Specific Terms 2 Indications 3 More General Terms 4 Additional Terms 5 References

More Specific Terms

• epleronone (Inspra)
• spironolactone (Aldactone)

Indications

• heart failure
• chronic renal disease due to diabetic nephropathy [2]

More General Terms

• hormone antagonist

Additional Terms

• K+ sparing diuretic
• mineralocorticoid receptor; MR; nuclear receptor subfamily 3 group C member 2 (NR3C2, MCR, MLR)

References

- Rossing K et al. Beneficial effects of adding spironolactone to recommended antihypertensive treatment in diabetic nephropathy. A randomized, double-masked, cross-over study. Diabetes Care 2005 Sep; 28:2106-12. PMID: [1] aldosterone receptor antagonist (aldosterone antagonist)