Aldosterone
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Contents |
Introduction
- Aldosterone secretion from the zona glomerulosa of the adrenal gland is stimulated by angiotensin II. The effect of aldosterone is predominantly on the distal tubular network of the kidney, effecting an increase in Na+ in exchange for K+. Effect mediated via mineralocorticoid receptor.
- Aldosterone may have deleterious effects on the myocardium. (see aldosterone antagonist)
More General Terms
Additional Terms
- adrenal steroid biosynthesis
- aldosterone in serum/plasma/urine
- aldosterone receptor antagonist (aldosterone antagonist)
- hyperaldosteronism
- hypoaldosteronism; mineralocorticoid deficiency
- mineralocorticoid receptor; MR; nuclear receptor subfamily 3 group C member 2 (NR3C2, MCR, MLR)
Internet Database
PubChem: 5839
PubChem: 521381
PubChem: 5317225
References
Tietz Textbook of Clinical Chemistry, 2nd ed. Burtis CA & Ashwood ER (eds), WB Saunders Co, Philadelphia PA, 1993, pg 1519
